Hippocampal Wnt Signaling
نویسندگان
چکیده
منابع مشابه
Wnt signaling in the regulation of adult hippocampal neurogenesis
In the adult brain new neurons are continuously generated mainly in two regions, the subventricular zone (SVZ) of the lateral ventricles and the subgranular zone (SGZ) in the hippocampal dentate gyrus. In the SGZ, radial neural stem cells (NSCs) give rise to granule cells that integrate into the hippocampal circuitry and are relevant for the plasticity of the hippocampus. Loss of neurogenesis i...
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The use of Wnt ligands for signaling between cells is a conserved feature of metazoan development. Activation of Wnt signal transduction pathways upon ligand binding can regulate diverse processes including cell proliferation, migration, polarity, differentiation and axon outgrowth. A 'canonical' Wnt signaling pathway has been elucidated in vertebrate and invertebrate model systems. In the cano...
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ژورنال
عنوان ژورنال: The Neuroscientist
سال: 2015
ISSN: 1073-8584,1089-4098
DOI: 10.1177/1073858415574728